Article Date: 11/1/2007

A Solution for Dropouts
contact lens management

A Solution for Dropouts

Solution disinfects and moisturizes with minimal ocular surface disruption.

MILE BRUJIC, O.D.

Some patients discontinue contact-lens (CL) wear due to the lens' poor disinfection capabilities and discomfort. I've discovered, however, that you can often prevent these causes of dropout by prescribing a contact-lens solution that properly disinfects and moisturizes with minimal ocular-surface disruption. This is why I often prescribe Opti-Free Replenish multipurpose disinfecting solution, from Alcon.

Disinfection

Opti-Free Replenish contains a preservative system comprised of two chemicals: polyquaternium-1 (Polyquad), which is a biguanide-free preservative antibacterial and myristamidopropyl dimethylamine (Aldox) 0.0005% — an antifungal and anti-acanthamoeba. Both enabled the solution to pass the Food and Drug Administrations (FDA) Stand Alone criteria to obtain labeling as a multi-purpose disinfecting solution.

In the Stand Alone test, CL care systems are challenged with three bacteria (pseudomonas aeruginosa, serratia marcescens and staphylococcus aureus). Two fungi (candida albicans and fusarium solani) also challenge systems. To pass the criteria, a solution must reduce the concentration of bacteria test organisms by 3 log units and yeast and fungi by 1 log unit. Opti-Free Replenish reduced bacteria concentrations by more than 3 log units and fungi by 3 log units.1

Moisturization

In a patient-satisfaction survey among 3,100 CL wearers (including asymptomatic subjects and those expressing prior discomfort/dryness), over 50% of patients could wear their lenses longer with the Opti-Free Replenish solution. This is presumably accomplished via Tearglyde, the solution's reconditioning agent. It is the combination of Tetronic-1304, the wetting agent found in Opti-Free Express, and C9-ED3A, a new moisture-enhancing molecule.1

Minimal ocular surface disruption

Some anecdotal and published reports have revealed that certain solution and contact-lens combinations can cause corneal staining. As a result, Gary Andrasko, O.D., who conducts research with contact lenses and solutions in Columbus, Ohio, began testing the level of corneal staining of an array of contact lens/multipurpose solutions. From this testing, he created a staining grid, which enables you to determine those combinations that may cause corneal staining. (www.staininggrid.com). Based on Dr. Andrasko's grid, Opti-Free Replenish causes little staining with any of the various types of soft contact lenses.

Opti-Free Replenish
FORMULATION: citrate, sodium chloride, sodium borate, propylene glycol, Tetronic® 1304, nonanoyl ethylenediaminetriacetic acid, polyquaternium-1 (Polyquad) 0.001% and myristamido propyldime-thylamine (Aldox) 0.0005%.
RECONDITIONING: Tearglyde Reconditioning System, which consists of Tetronic1304 and nonanoyl ethylenediaminetriacetic acid, which retains moisture on the lens surface throughout the lens-wear day.

Because Opti-Free Replenish properly disinfects and moisturizes with minimal ocular-surface disruption, it has enabled me to prevent many of my patients from discontinuing CL wear. OM

  1. Kern J, Napier L, Meadows D. Assessment of patient satisfaction with a new multi-purpose disinfecting solution using a patient outcome survey. Poster presented at American Optometric Association Annual meeting, Boston, 2007

MILE BRUJIC, O.D. IS A PARTNER IN A FOUR-LOCATION OPTOMETRY PRACTICE IN NORTHWEST OHIO. YOU CAN REACH HIM AT BRUJIC@PRODIGY.NET.



Optometric Management, Issue: November 2007