Article Date: 6/1/2008

Product Spotlight – NEW Blink<sup>®</sup> Tears Lubricating Eye Drops Relieve Dryness Symptoms

Product Spotlight — NEW Blink® Tears Lubricating Eye Drops Relieve Dryness Symptoms

New AMO™ Product

AMO's first dry eye product, Blink® Tears Lubricating Eye Drops, is a longer-lasting, preservative-free-in-the-eye drop with a tear film stabilizing formula and ophthalmic demulcent to relieve irritation stemming from ocular dryness.

Preservative-free in the Eye

Blink® Tears uses an oxidative preservative to protect the formulation in the bottle. The preservative breaks down into natural tear components when exposed to light.1 So it's preservative-free in the eye.

Tear Film Stability

Interferometry analysis shows that the formulation thickens the tear film when the eye is open and thins it when the eyelid closes.2 In this clinical trial, several subjects experienced retention times greater than 60 minutes.

The tear film provides a smooth refractive surface over the irregularities in the corneal topography. A stable tear film improves visual acuity.

Relief of Irritation

Demulcents are used to relieve the irritation brought on by ocular dryness. Blink® Tears employs polyethylene glycol (PEG-400) in a 0.25% concentration. In a clinical trial against a leading competitor with 0.4% PEG-400, Blink® Tears provided excellent relief and improved visual quality over time with less blurring.3

Surface Retention

The tear film is a hydrated mucin gel with its mucin concentration greatest at the epithelial surface.4 Lubricating drops are intended to wash away and dilute irritating or toxic substances in the tear film, but also may hydrate and wash away the mucin.

In premarket clinical trials, Blink® Tears had a longer retention time on the ocular surface.2


Ocular lubrication is essential for ocular health. Blink® Tears provides a cushion of moisture that creates longer retention time with less blurring, thereby increasing comfort and enhancing the quality of vision. With a formula that's preservative-free in the eye, it's nontoxic and nonirritating to the corneal surface. Its demulcent mitigates the irritation brought on by ocular dryness.

Patient Preference

Blink® Tears is well-suited for use by patients with a wide range of mild-to-moderate dry eye symptoms. In the clinical trials, patients overwhelmingly preferred Blink® Tears over their previous eye drops.3


  1. Noecker R. Effects of common ophthalmic preservatives on ocular health. Adv Therapy. 2001;18:205-215.
  2. Data on file, 2007. Interferometry clinical study. Advanced Medical Optics Inc.
  3. Data on file, Donnenfeld ED. Ophthalmic Consultants of Long Island, Rockville Center, NY.
  4. The Ocular Surface, 2007;5:166-167.
BLINK is a registered trademark and AMO, OCUPURE, EASY RUB and iLASIK are trademarks of Advanced Medical Optics, Inc. © 2008 by Advanced Medical Optics, Inc.

Optometric Management, Issue: June 2008