1. In vitro studies evaluated the rate of release of sodium hyaluronate (HA), a conditioning agent in the Biotrue® multi-purpose solution, from both conventional and silicone hydrogel contact lenses over a twenty-hour time period. HA was adsorbed on all traditional and silicone hydrogel contact lenses tested upon soaking in the solution overnight. HA is then released from the lenses throughout at least a twenty hour time period when rinsed with Hank's balanced salt solution at a rate mimicking tear secretions. The in-vitro performance of Biotrue® multi-purpose solution suggests that it will provide lens conditioning throughout a twenty hour time period.
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