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The Role of Corneal Hysteresis in Predicting Glaucoma Development

The Role of Corneal Hysteresis in Predicting Glaucoma Development

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Lowering of the intraocular pressure (IOP) has been shown to delay or prevent development of glaucomatous damage and its progression. However, as the disease frequently remains asymptomatic until relatively late stages, identification of subjects at high risk for developing glaucoma is important in order to allow early treatment and prevention of irreversible vision loss. Conversely, some patients are unnecessarily treated for high IOP when, in fact, glaucoma is not actually present.

Besides IOP, other factors such as age, central corneal thickness (CCT), disc hemorrhages, and structural and functional measures of the optic nerve have been identified as associated with risk of glaucoma development. In a recently published prospective investigation by Medeiros et al, baseline corneal hysteresis (CH) measurements, collected from a cohort of patients suspected of having the disease, were more predictive of development of glaucomatous visual field defects over time than other risk factors.

The study provides strong evidence that Corneal Hysteresis, over a 5-year period, is a risk factor for glaucoma development, and that for each 1 mmHg lower of Corneal Hysteresis, there was a 21% higher risk of glaucoma development. Read the full article here…