Clinical Scorecard: Managing Glaucoma With SLT
At a Glance
| Category | Detail |
|---|---|
| Condition | Open-angle glaucoma and secondary glaucomas including pseudoexfoliation and pigmentary dispersion glaucoma |
| Key Mechanisms | Selective laser trabeculoplasty (SLT) lowers intraocular pressure by cleaning and reinvigorating the trabecular meshwork to improve aqueous outflow |
| Target Population | Phakic and pseudophakic patients with open-angle or secondary glaucomas without cataract, corneal edema, or low IOP |
| Care Setting | Outpatient ophthalmology and optometry clinics |
Key Highlights
- SLT is effective as a first-line or adjunctive treatment to lower IOP and preserve visual function and quality of life
- Direct SLT (DSLT) is a noncontact, rapid automated laser procedure with similar efficacy but slightly less than conventional SLT
- Postoperative management no longer routinely requires steroids, NSAIDs, or in-office brimonidine; follow-up IOP checks at 8-12 weeks and new visual field/OCT baselines at 3-6 months
Guideline-Based Recommendations
Diagnosis
- Perform standard visual acuity and intraocular pressure exams
- Conduct gonioscopy to assess angle structure and pigmentation before SLT
Management
- Schedule SLT same-day or 2 to 4 weeks after glaucoma evaluation
- Prefer undilated 360º treatment in one or both eyes
- Avoid SLT in patients with cataract, corneal edema, or low IOP
- Consider discontinuing one topical glaucoma medication post-SLT if appropriate
Monitoring & Follow-up
- Check intraocular pressure at 8 to 12 weeks post-procedure
- Obtain new visual field and OCT baselines at 3 to 6 months after surgery
Risks
- Avoid SLT in eyes with cataract, corneal edema, or low intraocular pressure
Patient & Prescribing Data
Patients with open-angle and secondary glaucomas, both phakic and pseudophakic
SLT reduces treatment burden by potentially decreasing topical medication use; patient preferences vary with majority favoring drops but some preferring surgery
Clinical Best Practices
- Use SLT to enhance natural aqueous outflow via the trabecular meshwork
- Optometrists can perform DSLT and improve patient experience by explaining the procedure and stabilizing the head
- DSLT can be performed undilated with follow-up extended to 8-12 weeks
- Postoperative steroids, NSAIDs, and in-office brimonidine are not routinely necessary
References
- Los Angeles Latino Eye Study
- LiGHT Trial
- COAST Trial Abstract
- Melamed et al. SLT as primary treatment
- GLAUrious Trial Protocol
- Glaucoma Patient Treatment Preferences
- Market Scope Ophthalmic Market Trends US Glaucoma Edition Q4 2024
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